https://github.com/YukiMitsuta/shs4py

SHS4py is a Python-base script to calculate Scaled Hypersphere Searching method.

Mitsuta, Yuki, and Yasuteru Shigeta. “Analytical Method Using a Scaled Hypersphere Search for High-Dimensional Metadynamics Simulations.” Journal of chemical theory and computation 16.6 (2020): 3869-3878.